The Portuguese defender began a one-match ban after receiving a fifth booking of the season against Cheltenham in the FA Cup on November 27.
Fonte sat out the home defeat by Brentford but Saints' subsequent matches have all fallen victim to the weather.
He is set to go straight back into the back four with Dan Seaborne likely to give way.
Striker Rickie Lambert is fit after a dead leg while the postponements have given defender Frazer Richardson (thigh), midfielder Richard Chaplow (Achilles) and frontman Lee Barnard (groin) further time to recover from their injuries and all three will be checked over.
Winger Lee Holmes (ankle) remains a long-term absentee.